Photoprotective Effect of Tea and its Extracts against Ultraviolet Radiation-Induced Skin Disorders
نویسندگان
چکیده
Ultraviolet (UV) exposure induces photodamage of skin. It is a matter of concern that the level of UV radiation reaching the earth surface is increasing as a result of depletion of the stratospheric ozone, and climate change. It is urgently necessary to develop strategies to protect the skin from UV-induced injuries. Tea extracts are gaining increasing attention as a supplement in skin care products. However, the factors contributing to the photoprotective effects of tea extracts have not been systematically defined and conflicting results about the effect of tea extracts on photodamage have been reported. In this paper, the literature dealing with the use of tea and its extracts for the prevention of photodamage to the skin as well as the photoprotective effects of tea and its extracts have been highlighted. The potential chemopreventive agents in tea include catechins, caffeine, polysaccharides, apigenin and luteolin which inhibit, reverse or retard the process of the skin photodamage via their sunscreen and antioxidant properties, regulation of signal transduction pathway and gene expression, alleviation of DNA damage, and modulation immunological function are also presented. Existing gaps in this research field include incomplete clarity of photochemopreventive mechanism of tea, the adverse or side effects of tea extracts owing to residues or impurity and the instability of the functional components of tea during storage.
منابع مشابه
Anti-Inflammatory Effects of Aspalathus linearis and Cyclopia spp. Extracts in a UVB/Keratinocyte (HaCaT) Model Utilising Interleukin-1α Accumulation as Biomarker.
Ultraviolet B (UVB) radiation is one of the major predisposing risk factors of skin cancer. The anticancer and photoprotective effects of unoxidized rooibos (Aspalathus linearis) and honeybush (Cyclopia) herbal teas, containing high levels of dihydrochalones and xanthones, respectively, have been demonstrated in skin cancer models in vivo. In the current study, the anti-inflammatory effects of ...
متن کاملGreen tea and skin cancer: photoimmunology, angiogenesis and DNA repair.
Human skin is constantly exposed to numerous noxious physical, chemical and environmental agents. Some of these agents directly or indirectly adversely affect the skin. Cutaneous overexposure to environmental solar ultraviolet (UV) radiation (290-400 nm) has a variety of adverse effects on human health, including the development of melanoma and nonmelanoma skin cancers. Therefore, there is a ne...
متن کاملThe green tea polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage.
BACKGROUND Antioxidant compounds in green tea may be able to protect against skin carcinogenesis and it is of interest to investigate the mechanisms involved. A study was therefore conducted to determine whether the isolated green tea polyphenol (-)-epigallocatechin gallate (EGCG) could prevent ultraviolet radiation (UVR)-induced DNA damage in cultured human cells. This work was then extended t...
متن کاملTopical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin.
BACKGROUND Tea polyphenols have been found to exert beneficial effects on the skin via their antioxidant properties. AIMS We sought to determine whether topical application of green tea or white tea extracts would prevent simulated solar radiation-induced oxidative damages to DNA and Langerhans cells that may lead to immune suppression and carcinogenesis. METHODS Skin samples were analysed ...
متن کاملVitis vinifera seeds extract for the modulation of cytosolic factors BAX-α and NF-kB involved in UVB-induced oxidative stress and apoptosis of human skin cells.
BACKGROUND AND AIMS The depletion of the ozone layer allows overexposure of the skin to UV radiation, which is prolonged due to the increasing life expectancy, together with inappropriate life habits contribute to the increasing incidence of cutaneous malignancies. Plant extracts with antioxidant capacities are frequently employed as a means to protect skin against ultraviolet (UV) radiations, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014